Juvenile Idiopathic Inflammatory Myopathy (J-IIM) (Previously Juvenile Dermatomyositis)

Recommendations:

IVIG is recommended when there is a lack of response or contraindication to corticosteroids, Methotrexate and/or Azathioprine therapy.

1st line: Corticosteroids and Methotrexate

2nd line: IVIG

3rd line: Cyclosporine

 

Dose:

Initial dose: Total dose of 2 g/kg divided over 2 days.

Maintenance dose: A systematic approach should be taken to determine minimum effective dose. Continued use should be based on objective measures of sustained effectiveness.

Maximum dose should not exceed 2 g/kg.