Acute disseminated encephalomyelitis (ADEM)

Specialty: Neurology

Recommendations:

IVIG is an option for monophasic ADEM when first-line therapy with high-dose corticosteroids fails or when there are contraindications to steroid use, and for treatment of relapsing ADEM to eliminate steroid dependency or for those patients who fail to respond, or have contraindications, to steroids.

Dose:

Adults: Total dose of 2 g/kg divided over 2 to 5 days.

Pediatric: Total dose of 2 g/kg divided over 2 days.