Lambert-Eaton myasthenic syndrome (LEMS)

Specialty: Neurology

Recommendations:

IVIG is an option for treatment of LEMS. Objective evidence of clinical improvement is needed for sustained use of IVIG.

Dose:

Initial dose: Total dose of 2 g/kg divided over 2 to 5 days.

Maintenance dose: a systematic approach should be taken to determine the minimum effective dose, and continued use of IVIG should be based on objective measures of its sustained effectiveness. The maximum dose of IVIG per treatment course should be 2 g/kg.