IVIG is recommended when there is a lack of response or contraindication to corticosteroids, Methotrexate and/or Azathioprine therapy.
1st line: Corticosteroids and Methotrexate
2nd line: IVIG
3rd line: Cyclosporine
Initial dose: Total dose of 2 g/kg divided over 2 days.
Maintenance dose: A systematic approach should be taken to determine minimum effective dose. Continued use should be based on objective measures of sustained effectiveness.
Maximum dose should not exceed 2 g/kg.