Pemphigus Vulgaris (PV) and Variants

Specialty: Dermatology


Consider IVIG when there is no response or a contraindication to corticosteroids, immunosuppressive agents or biologics (e.g. rituximab) in conjunction with one of the above.

First line therapy: cortiscosteroids

Second line: immunosuppressive agents

Third line: IVIG


Total dose 2 g/kg divided over 2 to 5 days every 4 weeks.

Dose every 6 weeks after 6 months of therapy.